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Clinical Epidemiology and Evidence Based Care

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January 11: I. Introduction to Clinical epidemiology and Evidence-Based Practice
January 18: II. Searching for Scientific Evidence
January 25: III. Bias & methodological design & measurements
February 1: IV. Diagnosis and Screening.
February 8: V. Prognosis
February 15: V. Therapy
February 15: Therapy
March 7: VIII. Systematic Reviews
March 14. IX. Clinical guidelines
March 28 Implementation of EB in Dental Practice
2011 Papers for Critical Appraisal
2012 Papers for Critical Appraisal
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Prosthodontics > Clinical Epidemiology and Evidence Based Care

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by Dr A JokstadNo presence information
 1/27/2012 6:48 PM

January 11: I. Introduction to Clinical epidemiology and Evidence-Based Practice

January 11:  I. Introduction to Clinical epidemiology and Evidence-Based Practice Web Part Menu
EBD in Fixed ProsthodonticsUse SHIFT+ENTER to open the menu (new window).
Jokstad A. In: A Textbook of Fixed Prosthodontics. The Scandinavian Aproach. Gothia: 2000
EBD in prosthodonticsUse SHIFT+ENTER to open the menu (new window).
Anderson JD. Need for evidence-based practice in prosthodontics. J Prosthet Dent 2000; 83: 58-65January 25: III. Bias & methodological design & measurementFebruary 29: VII. Aetiology, Causation March 28. X. Implementation of EB in Dental Practice& Harms EBD series in J Prosthet Dentistry.
EBM - a new approach to educationUse SHIFT+ENTER to open the menu (new window).
Evidence-Based Medicine Working Group. Evidence-based medicine. A new approach to teaching the practice of medicine. JAMA 1992 Nov 4;268(17):2420-5.. JAMA 1992 The first time the term "Evidence-based Medicine" appeared
Formulating questions in EBDUse SHIFT+ENTER to open the menu (new window).
Sathorn C, Parashos P. Questions and answers in evidence-based patient care. Br Dent J. 2007 Sep 22;203(6):309-19.
How to get startedKnowledge TranslationUse SHIFT+ENTER to open the menu (new window).
Carr AB, McGivney GP. Users' guides to the dental literature: how to get started. J Prosthet Dent. 2000 Jan;83(1):13-20. First paper in the J Prosthet Dentistry EBD series
lecture 1 ebm viewUse SHIFT+ENTER to open the menu (new window).
Powerpoint Presentation by Professor Jokstad View version
Review. EBDUse SHIFT+ENTER to open the menu (new window).
Ismail & Bader. EBD in clinical practice. J Am Dent Assoc 2004: 135: 78-
What is EBDUse SHIFT+ENTER to open the menu (new window).
Richards & Lawrence. What is EBD? Evid Based Dent 1998; 1: 7-10 Editorial in the first issue of the EBD Journal. http://www.nature.com/ebd/journal/v1/n1/index.html 

January 18: II. Searching for Scientific Evidence

January 18:  II. Searching for Scientific Evidence Web Part Menu
Bibliographic database searchesUse SHIFT+ENTER to open the menu (new window).
Whiting P, et al. Systematic reviews of test accuracy should search a range of databases to identify primary studies. J Clin Epidemiol. 2008 Apr;61(4):357-364
Retrieving RCTs using filtersUse SHIFT+ENTER to open the menu (new window).
McKibbon et al. Retrieving randomized controlled trials from medline: a comparison of 38 published search filters. Health Info Libr J. 2009 Sep;26(3):187-202. http://www.ncbi.nlm.nih.gov/pubmed?term=%22Wilczynski%20NL%22%5BAuthor%5D
Searching for evidence Jan2012 view
Powerpoint Presentation by Professor Jokstad View version

January 25: III. Bias & methodological design & measurements

January 25:  III. Bias & methodological design & measurements Web Part Menu
EBD lecture 3 2012 view
Powerpoint Presentation by Professor Jokstad View version
How to design trialsUse SHIFT+ENTER to open the menu (new window).
Elements to consider when writing a paper Developed by A Jokstad - feel free to send feedback for improvement Adopted from: Altman DG. Practical statistics for medical research. Chapman and Hall, London.  http://books.google.com/books?id=v-walRnRxWQC&dq 
MeasurementsUse SHIFT+ENTER to open the menu (new window).
Carr AB, McGivney GP. Measurement in dentistry. J Prosthet Dent. 2000 Mar;83(3):266-71 EBD series in J Prosthet Dentistry.
Research Design HierarchiesUse SHIFT+ENTER to open the menu (new window).
Jacob RF, Carr AB. Hierarchy of research design used to categorize the "strength of evidence" in answering clinical dental questions. J Prosthet Dent. 2000 Feb;83(2):137-52. EBD series in J Prosthet Dentistry

February 1: IV. Diagnosis and Screening.

February 1: IV. Diagnosis and Screening. Web Part Menu
1 Diagnosis Anthonappa eaUse SHIFT+ENTER to open the menu (new window).
Anthonappa RP, King NM, Rabie AB, Mallineni SK. Reliability of panoramic radiographs for identifying supernumerary teeth in children. Int J Paediatr Dent. 2012 Jan;22(1):37-43
1 Diagnosis Edlund eaUse SHIFT+ENTER to open the menu (new window).
Edlund M, Nair MK, Nair UP. Detection of vertical root fractures by using cone-beam computed tomography: a clinical study. J Endod. 2011 Jun;37(6):768-72.
Checklist for critical appraisal of paper on diagnostics or screeningUse SHIFT+ENTER to open the menu (new window).
Adopted from: Sackett et al. Evidence Based Medicine. Elsevier 2005.
Diagnostic test evaluationUse SHIFT+ENTER to open the menu (new window).
Eckert SE, Goldstein GR, Koka S. How to evaluate a diagnostic test. J Prosthet Dent. 2000 Apr;83(4):386-91. EBD series in J Prosthet Dentistry
Diagnostic TestsUse SHIFT+ENTER to open the menu (new window).
From the Public Health Resource Unit (PHRU). U.K.
Guide to Decision makingUse SHIFT+ENTER to open the menu (new window).
Needleman & Moles. A guide to decision making in evidence-based diagnostics. Periodontol 2000. 2005;39:164-77
Diagnosis critical appraisal 2012Use SHIFT+ENTER to open the menu (new window).
Powerpoint Presentation by Professor Jokstad View version
Presentation 1. Diagnosis and screeningUse SHIFT+ENTER to open the menu (new window).
Critical appraisal of: Edlund M, Nair MK, Nair UP. Detection of vertical root fractures by using cone-beam computed tomography: a clinical study. J Endod. 2011 Jun;37(6):768-72. Trish Lukat & Niloufar Amintavakoli
Presentation 2. Diagnosis and ScreeningUse SHIFT+ENTER to open the menu (new window).
Critical appraisal of: Anthonappa RP, King NM, Rabie BM, Mallineni SK. Reliability of panoramic radiographs for identifying supernumerary teeth in children  Int J Paediatric Dent 2012; 22 Natoosha Azizi & Laurene Yen

February 8: V. Prognosis

February 8:  V. Prognosis Web Part Menu
Checklist for critical appraisal of paper on prognosisUse SHIFT+ENTER to open the menu (new window).
Adopted from: Sackett et al. Evidence Based Medicine. Elsevier 2005
Cohort studies appraisalUse SHIFT+ENTER to open the menu (new window).
From the Public Health Resource Unit (PHRU). U.K.
Presentation 2. PrognosisUse SHIFT+ENTER to open the menu (new window).
Critical appraisal of: Kim  SS, Yeo  IS, Lee  SJ, Kim  DJ, Jang  BM, Kim  SH, Han JS. Clinical use of alumina-toughened zirconia abutments for implant-supported restoration: prospective cohort study of survival analysis. Clin. Oral. Impl. Res. 0, 2012/1-6 Mohamed Kandil & Waad Kheder
Presentation 1. PrognosisUse SHIFT+ENTER to open the menu (new window).
Critical appraisal of: Gilbert GH, Shelton BJ, Chavers LS, Bradford EH Jr. Predicting tooth loss during a population-based study: role of attachment level in the presence of other dental conditions. J Periodontol. 2002 Dec;73(12):1427-36. Maayan Inger & Sari Hershenfield
Prognosis 1 Perio Gilbert eaUse SHIFT+ENTER to open the menu (new window).
Gilbert GH, Shelton BJ, Chavers LS, Bradford EH Jr. Predicting tooth loss during a population-based study: role of attachment level in the presence of other dental conditions. J Periodontol. 2002 Dec;73(12):1427-36.
Prognosis 2 Zirconia PaperUse SHIFT+ENTER to open the menu (new window).
Kim  SS, Yeo  IS, Lee  SJ, Kim  DJ, Jang  BM, Kim  SH, Han JS. Clinical use of alumina-toughened zirconia abutments for implant-supported restoration: prospective cohort study of survival analysis. Clin. Oral. Impl. Res. 0, 2012/1-6
Prognosis 2012Use SHIFT+ENTER to open the menu (new window).
Powerpoint Presentation by Professor Jokstad View version
PrognosisUse SHIFT+ENTER to open the menu (new window).
Anderson JD, Zarb GA. Evidence-based dentistry: prognosis. J Prosthet Dent. 2000 May;83(5):495-500 EBD series in J Prosthet Dentistry

February 15: VI. Therapy

February 15: VI. Therapy Web Part Menu
Checklist for critical appraisal of paper on InterventionUse SHIFT+ENTER to open the menu (new window).
Adopted from: Sackett et al. Evidence Based Medicine. Elsevier 2005
Presentation 1 - Anaesth 2012 - Mason et al. RCT on LidocaineUse SHIFT+ENTER to open the menu (new window).
Critical appraisal of: Mason R, Drum M, Reader A, Nusstein J, Beck M.. J Endod. 2009 Sep;35(9):1173-7. Joonyoung Ji & Michelle Wong
Presentation 2 - TherapyUse SHIFT+ENTER to open the menu (new window).
Critical appraisal of: Barcelos et al. The influence of smear layer removal on primary tooth pulpectomy outcome: a 24-month, double-blind, randomized, and controlled clinical trial evaluation. Int J Paediatr Dent  2011 Peter Bozavikov, Kamil Kolosowski
RCT appraisalsUse SHIFT+ENTER to open the menu (new window).
From the Public Health Resource Unit (PHRU). U.K.
Therapy 1 Anaesthesia Paper MasonUse SHIFT+ENTER to open the menu (new window).
Mason R, Drum M, Reader A, Nusstein J, Beck M. A prospective, randomized, double-blind comparison of 2% lidocaine with 1:100,000 and 1:50,000 epinephrine and 3% mepivacaine for maxillary infiltrations. J Endod. 2009 Sep;35(9):1173-7
Therapy 2 Pulpotomy BarcelosUse SHIFT+ENTER to open the menu (new window).
Barcelos R, Tannure PN, Gleiser R, Luiz RR, Primo LG. The influence of smear layer removal on primary tooth pulpectomy outcome: a 24-month, double-blind, randomized, and controlled clinical trial evaluation. Int J Paediatr Dent  2011
Therapy 2012Use SHIFT+ENTER to open the menu (new window).
Powerpoint Presentation by Professor Jokstad View version

February 29: VII. Aetiology, Causation & Harm

February 29: VII. Aetiology, Causation & Harm Web Part Menu
Aetiology 1 PerioUse SHIFT+ENTER to open the menu (new window).
Bollen AM. Effects of malocclusions and orthodontics on periodontal health: evidence from a systematic review. J Dent Educ. 2008 Aug;72(8):912-8
Aetiology 2 PediatricUse SHIFT+ENTER to open the menu (new window).
Mamie C, Habre W, Delhumeau C, Argiroffo CB, Morabia A. Incidence and risk factors of perioperative respiratory adverse events in children undergoing elective surgery. Paediatr Anaesth. 2004 Mar;14(3):218-24
Bradford Hill Causation criteria 1965Use SHIFT+ENTER to open the menu (new window).
Hill AB: The environment and disease: association or causation? Proc R Soc Med 1965, 58:295-300 A classic paper!
Case Control Studies appraisalUse SHIFT+ENTER to open the menu (new window).
From the Public Health Resource Unit (PHRU). U.K.
Aetiology 2012Use SHIFT+ENTER to open the menu (new window).
Powerpoint Presentation by Professor Jokstad View version
Evans Postulates for CausationUse SHIFT+ENTER to open the menu (new window).
Evans AS (May 1976). "Causation and disease: the Henle-Koch postulates revisited". Yale J Biol Med 1976; 49 (2): 175–95. A Classic Paper!
HarmUse SHIFT+ENTER to open the menu (new window).
Jacob RF, Lloyd PM. How to evaluate a dental article about harm. J Prosthet Dent. 2000 Jul;84(1):8-16 EBD series in J Prosthet Dentistry
STROBE_checklist_v4_case-control[1]Use SHIFT+ENTER to open the menu (new window).
STROBE Statement Checklist of items that should be included in reports of case-control studies
STROBE_checklist_v4_cohort[1]Use SHIFT+ENTER to open the menu (new window).
STROBE Statement— Checklist of items that should be included in reports of cohort studies
STROBE_checklist_v4_combined[1]Use SHIFT+ENTER to open the menu (new window).
STROBE Statement Checklist of items that should be included in reports of observational studies
STROBE_checklist_v4_cross-sectional[1]Use SHIFT+ENTER to open the menu (new window).
STROBE Statement— Checklist of items that should be included in reports of cross-sectional studies

March 7: VIII. Systematic Reviews

March 7: VIII. Systematic Reviews Web Part Menu
Checklist for critical appraisal of reviewsUse SHIFT+ENTER to open the menu (new window).
Adopted from: Sackett et al. Evidence Based Medicine. Elsevier 2005
Presentation 1. Systematic ReviewUse SHIFT+ENTER to open the menu (new window).
Critical appraisal of: Impact of the Quality of Coronal Restoration versus the quality of root canal fillings on Success of Root Canal Treatment: A Systematic Review and Meta-Analysis Kinga Baskai and Gillian Layton
Presentation 2. Systematic ReviewUse SHIFT+ENTER to open the menu (new window).
Critical appraisal of: Evaluation of methodology and quality characteristics of systematic reviews in orthodontics Bronsen Schliep and Kevin Knowlton
Prisma ChecklistUse SHIFT+ENTER to open the menu (new window).
27-item checklist of SR reporting quality
PrismaFlowUse SHIFT+ENTER to open the menu (new window).
Prisma flow diagram
Review. Systematic Reviews in DentistryUse SHIFT+ENTER to open the menu (new window).
Bader J, et al. Survey of systematic reviews in dentistry. J Am Dent Assoc. 2004 Apr;135(4):464-73.
Review. Systematic ReviewsUse SHIFT+ENTER to open the menu (new window).
Needleman IG.  A guide to systematic reviews. J Clin Periodontol. 2002;29 Suppl 3:6-9;
Reviews 2012Use SHIFT+ENTER to open the menu (new window).
Powerpoint Presentation by Professor Jokstad View version
ReviewsUse SHIFT+ENTER to open the menu (new window).
Felton DA, Lang BR. The overview: an article that interrogates the literature. J Prosthet Dent. 2000 Jul;84(1):17-21. EBD series in J Prosthet Dentistry
SR 1 Endo Coronal GillenUse SHIFT+ENTER to open the menu (new window).
Gillen BM, Looney SW, Gu LS, Loushine BA, Weller RN, Loushine RJ, Pashley DH, Tay FR. Impact of the quality of coronal restoration versus the quality of root canal fillings on success of root canal treatment: a systematic review and meta-analysis. J Endod
SR 2 Ortho qualityUse SHIFT+ENTER to open the menu (new window).
Papageorgiou SN, Papadopoulos MA, Athanasiou AE. Evaluation of methodology and quality characteristics of systematic reviews in orthodontics. Orthod Craniofac Res. 2011 Aug;14(3):116-37
Systematic Reviews AppraisalUse SHIFT+ENTER to open the menu (new window).
Critical Appraisal Skills Programme (CASP). From the Public Health Resource Unit (PHRU). U.K.
SystematicReviewsReplaceDeNovoUse SHIFT+ENTER to open the menu (new window).
White CM, Ip S, McPheeters M, et al. Using existing systematic reviews to replace de novo processes in conducting Comparative Effectiveness Reviews. In: Agency for Healthcare Research and Quality. Methods Guide for Comparative Effectiveness Reviews [poste

March 14. IX. Clinical guidelines

March 14. IX. Clinical guidelines Web Part Menu
2012 guidelinesUse SHIFT+ENTER to open the menu (new window).
Powerpoint Presentation by Professor Jokstad View version
Checklist for critical appraisal of Clinical GuidelinesUse SHIFT+ENTER to open the menu (new window).
Adopted from: Sackett et al. Evidence Based Medicine. Elsevier 2005
Presentation 1 Clinical GuidelinesUse SHIFT+ENTER to open the menu (new window).
Critical appraisal of: Momoi Y, Hayashi M, Fujitani M, Fukushima M, et al. Clinical guidelines for treating caries in adults following a minimal intervention policy-Evidence and consensus based report. J Dent. 2012 Feb;40(2):95-105 Aimee Varughese and Rae Castro
Presentation 2 Clinical GuidlinesUse SHIFT+ENTER to open the menu (new window).
van den Berg AD, Palmer NO. An Investigation of West Sussex General Dental Practitioners' Awareness, Attitudes and Adherence to NICE Dental Recall Guidelines. Prim Dent Care. 2012 Jan;19(1):11-22. Mahmoud Al-Dajani & Vinay Pilly & Joe Onigbinde

March 28. X. Implementation of EB in Dental Practice

March 28. X. Implementation of EB in Dental Practice Web Part Menu
1316.fullUse SHIFT+ENTER to open the menu (new window).
Rugh JD, Sever N, Glass BJ, Matteson SR. Transferring evidence-based information from dental school to practitioners: a pilot "academic detailing" program involving dental students. J Dent Educ. 2011 Oct;75(10):1316-22.
epidemiologypresentationUse SHIFT+ENTER to open the menu (new window).
Antibiotic Prophylaxis in dentistry: part I. A Qualitative study of professionals’ views on the NICE guideline.
Implementation McGlone ea 2001Use SHIFT+ENTER to open the menu (new window).
McGlone P, Watt R, Sheiham A. Evidence-based dentistry: an overview of the challenges in changing professional practice. Br Dent J. 2001 Jun 23;190(12):636-9
Implementation Paper 2. Wardh. SwedenUse SHIFT+ENTER to open the menu (new window).
Wårdh I, et al. Which evidence has an impact on dentists' willingness to change their behavior? J Evid Based Dent Pract 2009;9(4):197-205
Qualitative Studies appraisalUse SHIFT+ENTER to open the menu (new window).
From the Public Health Resource Unit (PHRU). U.K.
Shaw Conway 2010Use SHIFT+ENTER to open the menu (new window).
Shaw D, Conway DI. Pascal's Wager, infective endocarditis and the "no-lose" philosophy in medicine. Heart. 2010 Jan;96(1):15-8

April 3. Final Test

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Glossaries

Glossaries Web Part Menu
  Glossary of Cochrane Collaboration and research terms
  Glossary of EBM Terms. University Health Network
  The Clinical Evidence glossary
  University of Oxford, UK. Bandolier

Guidelines Development

Guidelines Development Web Part Menu
  AGREE Instrument
  Methodology - Canadian Agency for Drugs and Technologies in Health

Knowledge Translation

Knowledge Translation Web Part Menu
  CIHR KT Clearinghouse
  UofT Joint Program in Knowledge Translation
  U McMaster

Research that has changed practice

Research that has changed practice Web Part Menu
  Project IMPACT: Important Achievements of Clinical Trials
  The James Lind Library

Standards for Reporting

Standards for Reporting Web Part Menu
  STROBE - Observational Studies
  CONSORT RCTs
  STARD - Diagnostic Tests
  PRISMA - SRs & Meta-analyses
  EQUATOR Network -- Repository
  STREGA - Genetic Associations

EBM Resources

EBM Resources Web Part Menu
  ADA Center for Evidence Based Dentistry Resources
  Centre for Evidence-Based Dentistry, Oxford, UK
  The Cochrane Oral Health Review Group, Manchester, UK
  The Forsyth Center for Evidence-Based Dentistry, Boston, MA, USA
  Journal of Evidence-Based Dentistry, Nature Publishing
  The Journal of Evidence-Based Dental Practice, Elsevier Science
  A Jokstad Lectures on EB Practice & Clinical Epidemiology
  Virtual Centre for Improving Oral Health through Evidence-Based Dentistry' (vC-IOH), Dundee, UK
  AMSTAR criteria for SRs
  Centre for Evidence-based Medicine, University Health Network, Canada
  The Centre for Health Evidence, Alberta, Canada
  Cochrane Handbook for Systematic Reviews of Interventions
  Duke University, N.C. USA
  The National Collaborating Centre for Methods and Tools (NCCMT)
  Evidence Based Medicine Toolkit, University of Alberta, Canada
  Italian EB Health Website . Many links to EB papers
  McMaster University Health Information Research Unit
  PedsCCM: The Pediatric Critical Care Website:
  North Carolina EBP Center of Excellence

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